1-alpha-hydroxylase
25-Hydroxyvitamin D 1-alpha-hydroxylase (VD 1A hydroxylase) also known as calcidiol 1-monooxygenase[5] or cytochrome p450 27B1 (CYP27B1) or simply 1-alpha-hydroxylase is a cytochrome P450 enzyme that in humans is encoded by the CYP27B1 gene. [6][7][8] 25-hydroxyvitamin D3 1-alpha hydroxylase (CYP27B1) is an enzyme that catalyzes the conversion of 25-hydroxyvitamin D3 to its active form, 1,25-dihydroxyvitamin D3, playing a crucial role in regulating calcium homeostasis and epidermal differentiation. The vitamin D3 1alpha-hydroxylase gene and its regulation by ... - PubMed 17 alpha-hydroxylase deficiency is a rare congenital adrenal hyperplasia resulting from inactivating mutations in the CYP17A1 gene. This enzyme deficiency disrupts steroidogenesis by impairing both ... ascopubs.org: Presentation of splice variants of 1-alpha-hydroxylase in MCF-7 breast cancer cells
Phase I evaluation of abiraterone acetate (CB7630), a 17 alpha hydroxylase C17,20-Lyase inhibitor in androgen-independent prostate cancer (AiPC) This occurs in the renal proximal tubule via the regulation of the expression of two enzymes. 1-alpha-hyrdoxylase encoded by CYP27B1 results in the 1-hydroxylation of calcitriol and thus more active vitamin D.
Rat CYP7A1(Cholesterol 7-Alpha-Hydroxylase) ELISA Kit-Reed Biotech Ltd
