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The meaning of GERM is a small mass of living substance capable of developing into an organism or one of its parts. How to use germ in a sentence. Germs live everywhere. There are germs, also called microbes, in the air; on food, plants and animals; and in the soil and water. Germs are on just about every surface, including the human body. Most germs cause no harm. The immune system protects against things that cause infections, called infectious agents. But some germs keep changing to get past the immune system's defenses. Knowing how ... GERM meaning: 1. a very small organism that causes disease: 2. a small amount, usually one that develops into…. Learn more. Definition of germ noun in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more. Define germ. germ synonyms, germ pronunciation, germ translation, English dictionary definition of germ. n. 1. Biology A small mass of protoplasm or cells from which a new organism or one of its parts may develop. 2. The earliest form of an organism; a seed,...

germ: A small mass of protoplasm or cells from which a new organism or one of its parts may develop. GERM definition: a microorganism, especially when disease-producing; microbe. See examples of germ used in a sentence.