where would the enzyme topoisomerase attach during dna replication

A series of experiments reveal that a germline mutation of the enzyme topoisomerase II B affects the movement of proteins in the nuclei of cells with this mutation The processes of DNA replication and ... The solution to DNA's topological problems comes in the form of enzymes called topoisomerases that serve as "swivels" and allow the molecule to perform its requisite acrobatics. Type I topoisomerase ... Researchers have identified two natural compounds, patulin and xestoquinol, as new inhibitors of the enzyme topoisomerase 1, a key element in the correct functioning of DNA. The finding, published in ... Science Daily: Structure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugs Structure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugs

An enzyme is a biological catalyst and is almost always a protein. It speeds up the rate of a specific chemical reaction in the cell. The enzyme is not destroyed during the reaction and is used over and over. A cell contains thousands of different types of enzyme molecules, each specific to a particular chemical reaction.